Glucokinase and Glycemic Diseases Book For Free Purchase

Glucokinase and Glycemic Diseases - This book is also packed with tips and expert advice that will keep you feeling enjoy released by Karger Medical and Scientific Publishers on 2004 referenced for you if you want book with category Medical / Endocrinology & Metabolism, . - This book is also packed with tips and expert advice that will keep you feeling enjoy composed by Franz M. Matschinsky, Mark A. Magnuson, with page count 406 Pages. you can found book detail at here

Download Glucokinase and Glycemic Diseases From Basics to Novel Therapeutics all pages

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ISBN: 9783805577441


The glucose-phosphorylating enzyme glucokinase (also known as hexokinase IV) plays a preeminent role as a glucose sensor and regulatory metabolic enzyme. The implications of this central position of glucokinase for the understanding and treatment of diabetes mellitus are far reaching. This book addresses the molecular and human genetic, as well as the physiological-chemical and pharmacological aspects of the role glucokinase plays in glucose homeostasis and diseases of glucose metabolism, and how the enzyme serves as the drug target for the treatment of diabetes mellitus. The collection of assays by a team of internationally renowned authors includes basic science chapters dealing with the enzymology, structure and the kinetics of hexokinases, essays describing the biochemical genetics of glucokinase-linked hypo- and hyperglycemia syndromes, and papers that discuss the diverse roles of the enzyme in a variety of tissues. Finally, the book contains the latest information on the recently discovered class of weight drugs that activate glucokinase (i.e. glucokinase activators or GKAs). This volume is of great interest to basic and clinical diabetes researchers, geneticists, biochemists, physiologists and pharmacologists.


Glucokinase and Glycemic Diseases



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